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Evidence of variable human Fcγ receptor-Fc affinities across differentially-complexed IgG
Antibody-mediated effector functions are widely considered to unfold according to an associative model of IgG-Fcγ receptor (FcγR) interactions. The associative model presupposes that Fc receptors cannot discriminate antigen-bound IgG from free IgG in solution and have equivalent affinities for each....
Autores principales: | Crowley, Andrew R., Mehlenbacher, Matthew R., Sajadi, Mohammad M., DeVico, Anthony L., Lewis, George K., Ackerman, Margaret E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324447/ https://www.ncbi.nlm.nih.gov/pubmed/37405954 http://dx.doi.org/10.1080/19420862.2023.2231128 |
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