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Synergism of calycosin and bone marrow-derived mesenchymal stem cells to combat podocyte apoptosis to alleviate adriamycin-induced focal segmental glomerulosclerosis

BACKGROUND: Bone marrow-derived mesenchymal stem cells (MSCs) show podocyte-protective effects in chronic kidney disease. Calycosin (CA), a phytoestrogen, is isolated from Astragalus membranaceus with a kidney-tonifying effect. CA preconditioning enhances the protective effect of MSCs against renal...

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Detalles Bibliográficos
Autores principales: Hu, Qiong-Dan, Tan, Rui-Zhi, Zou, Yuan-Xia, Li, Jian-Chun, Fan, Jun-Ming, Kantawong, Fahsai, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324505/
https://www.ncbi.nlm.nih.gov/pubmed/37424951
http://dx.doi.org/10.4252/wjsc.v15.i6.617