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The H2-A Class II molecule α/β-chain cis-mismatch severely affects cell surface expression, selection of conventional CD4(+) T cells and protection against TB infection
INTRODUCTION: To dissect the role of the part of the H2 complex comprised of the MHC-II genes in the control of tuberculosis (TB) infection, we previously established a panel of recombinant congenic mouse strains bearing different segments of the H2 (j) haplotype on the B6 (H2 (b)) genetic backgroun...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324577/ https://www.ncbi.nlm.nih.gov/pubmed/37426653 http://dx.doi.org/10.3389/fimmu.2023.1183614 |