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The H2-A Class II molecule α/β-chain cis-mismatch severely affects cell surface expression, selection of conventional CD4(+) T cells and protection against TB infection

INTRODUCTION: To dissect the role of the part of the H2 complex comprised of the MHC-II genes in the control of tuberculosis (TB) infection, we previously established a panel of recombinant congenic mouse strains bearing different segments of the H2 (j) haplotype on the B6 (H2 (b)) genetic backgroun...

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Detalles Bibliográficos
Autores principales: Logunova, Nadezhda, Kapina, Marina, Kondratieva, Elena, Apt, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324577/
https://www.ncbi.nlm.nih.gov/pubmed/37426653
http://dx.doi.org/10.3389/fimmu.2023.1183614

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