Long-term menopause exacerbates vaginal wall support injury in ovariectomized rats by regulating amino acid synthesis and glycerophospholipid metabolism

PURPOSE: Menopause is a risk factor for pelvic organ prolapse (POP) and is frequently associated with diminished vaginal wall support. To uncover relevant molecular mechanisms and provide potential therapeutic targets, we evaluated changes in the transcriptome and metabolome of the vaginal wall in o...

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Detalles Bibliográficos
Autores principales: Yu, Xia, He, Li, Lin, Wenyi, Zheng, Xuemei, Zhang, Ling, Yu, Bo, Wang, Yanjun, Yang, Zhenglin, Lin, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324610/
https://www.ncbi.nlm.nih.gov/pubmed/37424873
http://dx.doi.org/10.3389/fendo.2023.1119599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324610/
https://www.ncbi.nlm.nih.gov/pubmed/37424873
http://dx.doi.org/10.3389/fendo.2023.1119599

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