Cargando…

Long-term menopause exacerbates vaginal wall support injury in ovariectomized rats by regulating amino acid synthesis and glycerophospholipid metabolism

PURPOSE: Menopause is a risk factor for pelvic organ prolapse (POP) and is frequently associated with diminished vaginal wall support. To uncover relevant molecular mechanisms and provide potential therapeutic targets, we evaluated changes in the transcriptome and metabolome of the vaginal wall in o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Xia, He, Li, Lin, Wenyi, Zheng, Xuemei, Zhang, Ling, Yu, Bo, Wang, Yanjun, Yang, Zhenglin, Lin, Yonghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324610/ https://www.ncbi.nlm.nih.gov/pubmed/37424873 http://dx.doi.org/10.3389/fendo.2023.1119599

Ejemplares similares

Metabolic remodeling of glycerophospholipids acts as a signature of dulaglutide and liraglutide treatment in recent-onset type 2 diabetes mellitus
por: Du, Juan, et al.
Publicado: (2023)

Serum Glycerophospholipid Profile in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
por: Gai, Xiaoyan, et al.
Publicado: (2021)

Tissue Composition and Biomechanical Property Changes in the Vaginal Wall of Ovariectomized Young Rats
por: Mao, Meng, et al.
Publicado: (2019)

Emerging trends on the mechanism of pelvic organ prolapse from 1997 to 2022: visualization and bibliometric analysis
por: Yu, Xia, et al.
Publicado: (2023)

Ostarine and Ligandrol Improve Muscle Tissue in an Ovariectomized Rat Model
por: Roch, Paul Jonathan, et al.
Publicado: (2020)

Role of AMH in Prediction of Menopause
por: de Kat, Annelien C., et al.
Publicado: (2021)

Sarcopenia and Menopause: The Role of Estradiol
por: Geraci, Annalisa, et al.
Publicado: (2021)

Effects of Total Flavonoids of Epimedium on Bone Marrow Adipose Tissue in Ovariectomized Rats
por: Chen, Lei, et al.
Publicado: (2022)

Hydrogen saline water accelerates fracture healing by suppressing autophagy in ovariectomized rats
por: Guo, Jialiang, et al.
Publicado: (2022)

Water Extract of Rhizoma Drynaria Selectively Exerts Estrogenic Activities in Ovariectomized Rats and Estrogen Receptor-Positive Cells
por: Zhou, Liping, et al.
Publicado: (2022)

Mediterranean Diet: What Are the Consequences for Menopause?
por: Vetrani, Claudia, et al.
Publicado: (2022)

Fecal microbiota transplantation mitigates vaginal atrophy in ovariectomized mice
por: Huang, Jia, et al.
Publicado: (2021)

Vaginal Health in Menopausal Women
por: Alvisi, Stefania, et al.
Publicado: (2019)

SAT-238 Predictors Of Vaginal/Uterine Bleeding With Oral TX-001HR (Estradiol and Progesterone) Capsules Taken For Menopausal Vasomotor Symptoms
por: Constantine, Ginger, et al.
Publicado: (2019)

Overall adjustment acupuncture improves osteoporosis and exerts an endocrine-modulating effect in ovariectomized rats
por: Li, Xiang, et al.
Publicado: (2022)

Menopausal Hormone Replacement Therapy and the Risk of Ovarian Cancer: A Meta-Analysis
por: Liu, Yang, et al.
Publicado: (2019)

Menopausal hormone therapy does not improve some domains of memory: A systematic review and meta-analysis
por: Chen, Lin, et al.
Publicado: (2022)

Detection of the Disorders of Glycerophospholipids and Amino Acids Metabolism in Lung Tissue From Male COPD Patients
por: Huang, Qian, et al.
Publicado: (2022)

Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism
por: Li, Ming, et al.
Publicado: (2023)

Glycerophospholipid Supplementation as a Potential Intervention for Supporting Cerebral Structure in Older Adults
por: Reddan, Jeffery M., et al.
Publicado: (2018)

Glycerophospholipids pathways and chromosomal instability in gastric cancer: Global lipidomics analysis
por: Hung, Cheng-Yu, et al.
Publicado: (2019)

Spatial Distribution of Glycerophospholipids in the Ocular Lens
por: Pól, Jaroslav, et al.
Publicado: (2011)

Dynamics of the Ethanolamine Glycerophospholipid Remodeling Network
por: Zhang, Lu, et al.
Publicado: (2012)

Distribution of Glycerophospholipids in the Adult Human Lens
por: Seng, Jo Ann, et al.
Publicado: (2018)

Effect of Rhizoma Drynariae on differential gene expression in ovariectomized rats with osteoporosis based on transcriptome sequencing
por: Su, Hui, et al.
Publicado: (2022)

Combination of Red Clover and Hops Extract Improved Menopause Symptoms in an Ovariectomized Rat Model
por: Kim, Mi Ran, et al.
Publicado: (2020)

S-equol Exerts Estradiol-Like Anorectic Action with Minimal Stimulation of Estrogen Receptor-α in Ovariectomized Rats
por: Nishimura, Yuri, et al.
Publicado: (2017)

Anti-osteoporosis mechanism of resistance exercise in ovariectomized rats based on transcriptome analysis: a pilot study
por: Wang, Qing, et al.
Publicado: (2023)

Functional and molecular neuroimaging of menopause and hormone replacement therapy
por: Comasco, Erika, et al.
Publicado: (2014)

Review of mendelian randomization studies on age at natural menopause
por: Zhang, Xiao, et al.
Publicado: (2023)

Novel Glycerophospholipid, Lipo- and N-acyl Amino Acids from Bacteroidetes: Isolation, Structure Elucidation and Bioactivity
por: Bill, Mona-Katharina, et al.
Publicado: (2021)

Effect of Menopausal Hormone Therapy on the Vaginal Microbiota and Genitourinary Syndrome of Menopause in Chinese Menopausal Women
por: Geng, Lulu, et al.
Publicado: (2020)

Effects of Icariin on Modulating Gut Microbiota and Regulating Metabolite Alterations to Prevent Bone Loss in Ovariectomized Rat Model
por: Wang, Shanshan, et al.
Publicado: (2022)

Genomic-Metabolomic Associations Support the Role of LIPC and Glycerophospholipids in Age-Related Macular Degeneration
por: Lains, Ines, et al.
Publicado: (2021)

Behavioral, Oxidative, and Biochemical Effects of Omega-3 on an Ovariectomized Rat Model of Menopause
por: Da Rocha, Renata Vinholes Oliveira, et al.
Publicado: (2021)

Tissue-Specific Effects of Loss of Estrogen during Menopause and Aging
por: Wend, Korinna, et al.
Publicado: (2012)

The Importance of Glycerophospholipid Production to the Mutualist Symbiosis of Trypanosomatids
por: de Azevedo-Martins, Allan C., et al.
Publicado: (2021)

Dynamic modulations of sphingolipids and glycerophospholipids in COVID‐19
por: Kurano, Makoto, et al.
Publicado: (2022)

The catalytic and structural basis of archaeal glycerophospholipid biosynthesis
por: de Kok, Niels A. W., et al.
Publicado: (2022)

Construction of a focal adhesion signaling pathway-related ceRNA network in pelvic organ prolapse by transcriptome analysis
por: Yu, Xia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jd7i3khc3rtl808lrhr89tj59j