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Targeting cyclin D1 as a therapeutic approach for papillary thyroid carcinoma

Cyclin D1 functions as a mitogenic sensor that specifically binds to CDK4/6, thereby integrating external mitogenic inputs and cell cycle progression. Cyclin D1 interacts with transcription factors and regulates various important cellular processes, including differentiation, proliferation, apoptosi...

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Detalles Bibliográficos
Autores principales: Cai, Wei, Shu, Lin-Zhen, Liu, Ding-Jie, Zhou, Lv, Wang, Meng-Meng, Deng, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324616/
https://www.ncbi.nlm.nih.gov/pubmed/37427143
http://dx.doi.org/10.3389/fonc.2023.1145082