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Targeting cyclin D1 as a therapeutic approach for papillary thyroid carcinoma
Cyclin D1 functions as a mitogenic sensor that specifically binds to CDK4/6, thereby integrating external mitogenic inputs and cell cycle progression. Cyclin D1 interacts with transcription factors and regulates various important cellular processes, including differentiation, proliferation, apoptosi...
Autores principales: | Cai, Wei, Shu, Lin-Zhen, Liu, Ding-Jie, Zhou, Lv, Wang, Meng-Meng, Deng, Huan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324616/ https://www.ncbi.nlm.nih.gov/pubmed/37427143 http://dx.doi.org/10.3389/fonc.2023.1145082 |
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