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Community detection in empirical kinase networks identifies new potential members of signalling pathways

Phosphoproteomics allows one to measure the activity of kinases that drive the fluxes of signal transduction pathways involved in biological processes such as immune function, senescence and cell growth. However, deriving knowledge of signalling network circuitry from these data is challenging due t...

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Detalles Bibliográficos
Autores principales: Basanta, Celia De Los Angeles Colomina, Bazzi, Marya, Hijazi, Maruan, Bessant, Conrad, Cutillas, Pedro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325051/
https://www.ncbi.nlm.nih.gov/pubmed/37352361
http://dx.doi.org/10.1371/journal.pcbi.1010459