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Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells

The viral hemagglutinins of conventional influenza A viruses (IAVs) bind to sialylated glycans on host cell surfaces for attachment and subsequent infection. In contrast, hemagglutinins of bat-derived IAVs target major histocompatibility complex class II (MHC-II) for cell entry. MHC-II proteins from...

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Detalles Bibliográficos
Autores principales: Olajide, Okikiola M., Osman, Maria Kaukab, Robert, Jonathan, Kessler, Susanne, Toews, Lina Kathrin, Thamamongood, Thiprampai, Neefjes, Jacques, Wrobel, Antoni G., Schwemmle, Martin, Ciminski, Kevin, Reuther, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325068/
https://www.ncbi.nlm.nih.gov/pubmed/37410798
http://dx.doi.org/10.1371/journal.pbio.3002182