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Sequence- and structure-specific RNA oligonucleotide binding attenuates heterogeneous nuclear ribonucleoprotein A1 dysfunction

The RNA binding protein heterogeneous nuclear ribonucleoprotein A1 (A1) regulates RNA metabolism, which is crucial to maintaining cellular homeostasis. A1 dysfunction mechanistically contributes to reduced cell viability and loss, but molecular mechanisms of how A1 dysfunction affects cell viability...

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Detalles Bibliográficos
Autores principales: Clarke, Joseph P., Thibault, Patricia A., Fatima, Sakina, Salapa, Hannah E., Kalyaanamoorthy, Subha, Ganesan, Aravindhan, Levin, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325567/
https://www.ncbi.nlm.nih.gov/pubmed/37426420
http://dx.doi.org/10.3389/fmolb.2023.1178439