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Inhibition of synaptic transmission by anandamide precursor 20:4-NAPE is mediated by TRPV1 receptors under inflammatory conditions

Transient receptor potential ion channel, vanilloid subfamily, type 1 (TRPV1) cation channel, and cannabinoid receptor 1 (CB(1)) are essential in the modulation of nociceptive signaling in the spinal cord dorsal horn that underlies different pathological pain states. TRPV1 and CB(1) receptors share...

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Detalles Bibliográficos
Autores principales: Spicarova, Diana, Nerandzic, Vladimir, Muzik, David, Pontearso, Monica, Bhattacharyya, Anirban, Nagy, Istvan, Palecek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325575/
https://www.ncbi.nlm.nih.gov/pubmed/37426071
http://dx.doi.org/10.3389/fnmol.2023.1188503