High salt intake activates the hypothalamic–pituitary–adrenal axis, amplifies the stress response, and alters tissue glucocorticoid exposure in mice

AIMS: High salt intake is common and contributes to poor cardiovascular health. Urinary sodium excretion correlates directly with glucocorticoid excretion in humans and experimental animals. We hypothesized that high salt intake activates the hypothalamic–pituitary–adrenal axis activation and leads...

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Detalles Bibliográficos
Autores principales: Costello, Hannah M, Krilis, Georgios, Grenier, Celine, Severs, David, Czopek, Alicja, Ivy, Jessica R, Nixon, Mark, Holmes, Megan C, Livingstone, Dawn E W, Hoorn, Ewout J, Dhaun, Neeraj, Bailey, Matthew A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325699/
https://www.ncbi.nlm.nih.gov/pubmed/36368681
http://dx.doi.org/10.1093/cvr/cvac160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325699/
https://www.ncbi.nlm.nih.gov/pubmed/36368681
http://dx.doi.org/10.1093/cvr/cvac160

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