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Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

INTRODUCTION: Psilocybin is one of the most extensively studied psychedelic drugs with a broad therapeutic potential. Despite the fact that its psychoactivity is mainly attributed to the agonism at 5-HT(2A) receptors, it has high binding affinity also to 5-HT(2C) and 5-HT(1A) receptors and indirectl...

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Detalles Bibliográficos
Autores principales: Tylš, Filip, Vejmola, Čestmír, Koudelka, Vlastimil, Piorecká, Václava, Kadeřábek, Lukáš, Bochin, Marcel, Novák, Tomáš, Kuchař, Martin, Bendová, Zdeňka, Brunovský, Martin, Horáček, Jiří, Pálení ček, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325866/
https://www.ncbi.nlm.nih.gov/pubmed/37425017
http://dx.doi.org/10.3389/fnins.2023.1152578