Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes

AIMS: To explore the novel molecular mechanisms of histone deacetylase 4 (HDAC4) in chondrocytes via RNA sequencing (RNA-seq) analysis. METHODS: Empty adenovirus (EP) and a HDAC4 overexpression adenovirus were transfected into cultured human chondrocytes. The cell survival rate was examined by real-...

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Detalles Bibliográficos
Autores principales: Guo, Li, Guo, Hua, Zhang, Yuanyu, Chen, Zhi, Sun, Jian, Wu, Gaige, Wang, Yunfei, Zhang, Yang, Wei, Xiaochun, Li, Pengcui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Cartilage
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325875/
https://www.ncbi.nlm.nih.gov/pubmed/37414410
http://dx.doi.org/10.1302/2046-3758.127.BJR-2022-0279.R2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325875/
https://www.ncbi.nlm.nih.gov/pubmed/37414410
http://dx.doi.org/10.1302/2046-3758.127.BJR-2022-0279.R2

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