Cargando…

Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes

AIMS: To explore the novel molecular mechanisms of histone deacetylase 4 (HDAC4) in chondrocytes via RNA sequencing (RNA-seq) analysis. METHODS: Empty adenovirus (EP) and a HDAC4 overexpression adenovirus were transfected into cultured human chondrocytes. The cell survival rate was examined by real-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Li, Guo, Hua, Zhang, Yuanyu, Chen, Zhi, Sun, Jian, Wu, Gaige, Wang, Yunfei, Zhang, Yang, Wei, Xiaochun, Li, Pengcui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2023
Materias:	Cartilage
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325875/ https://www.ncbi.nlm.nih.gov/pubmed/37414410 http://dx.doi.org/10.1302/2046-3758.127.BJR-2022-0279.R2

Ejemplares similares

The role of histone deacetylase 4 during chondrocyte hypertrophy and endochondral bone development
por: Chen, Zhi, et al.
Publicado: (2020)

GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis
por: Wang, Helin, et al.
Publicado: (2022)

A mutation in SLC20A2 (c.C1849T) promotes proliferation while inhibiting hypertrophic differentiation in ATDC5 chondrocytes
por: Li, YiQiang, et al.
Publicado: (2020)

Decreased Peli1 expression attenuates osteoarthritis by protecting chondrocytes and inhibiting M1-polarization of macrophages
por: Mo, Haokun, et al.
Publicado: (2023)

Clinical evaluation after matrix-associated autologous chondrocyte transplantation: a comparison of four different graft types
por: Binder, Harald, et al.
Publicado: (2021)

Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage: a new tool for cartilage pathophysiology studies
por: Piñeiro-Ramil, María, et al.
Publicado: (2023)

The molecular mechanism study of COMP involved in the articular cartilage damage of Kashin-Beck disease
por: Ma, Mei, et al.
Publicado: (2020)

CircStrn3 targeting microRNA-9-5p is involved in the regulation of cartilage degeneration and subchondral bone remodelling in osteoarthritis
por: Li, Bin, et al.
Publicado: (2023)

Integrating genome-wide association study with regulatory SNP annotations identified novel candidate genes for osteoporosis
por: Jia, Yumeng, et al.
Publicado: (2023)

Global transcriptome analysis to identify critical genes involved in the pathology of osteoarthritis
por: Zhang, X., et al.
Publicado: (2018)

Rejuvenated ageing mesenchymal stem cells by stepwise preconditioning ameliorates surgery-induced osteoarthritis in rabbits
por: Zong, Zhixian, et al.
Publicado: (2020)

The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis
por: He, Chao-Peng, et al.
Publicado: (2022)

Interleukin-1 receptor antagonist protein (IL-1Ra) and miR-140 overexpression via pNNS-conjugated chitosan-mediated gene transfer enhances the repair of full-thickness cartilage defects in a rabbit model
por: Zhao, R., et al.
Publicado: (2019)

Whole-transcriptome sequencing of knee joint cartilage from osteoarthritis patients
por: Li, H., et al.
Publicado: (2019)

Molecular crosstalk between articular cartilage, meniscus, synovium, and subchondral bone in osteoarthritis
por: Wang, Maochun, et al.
Publicado: (2022)

Muscular forces affect the glycosaminoglycan content of joint cartilage: Unloading in human volunteers with the HEPHAISTOS lower leg orthosis
por: Ganse, Bergita, et al.
Publicado: (2015)

Dynamic shear analysis: a novel method to determine mechanical integrity of normal and torn human acetabular labra: Implications for prediction of outcome of repair
por: Woods, A. K., et al.
Publicado: (2018)

The effect of anti-inflammatory and antifibrotic agents on fibroblasts obtained from arthrofibrotic tissue: An in vitro and in vivo study
por: Tang, X., et al.
Publicado: (2018)

A novel organ culture model of a joint for the evaluation of static and dynamic load on articular cartilage
por: Lin, Y-C., et al.
Publicado: (2018)

Tranexamic acid toxicity in human periarticular tissues
por: McLean, M., et al.
Publicado: (2019)

Validation of joint space narrowing on plain radiographs and its relevance to partial knee arthroplasty: radiological and MRI data from the Osteoarthritis Initiative
por: Khury, Farouk, et al.
Publicado: (2021)

The effectiveness of platelet-rich plasma gel on full-thickness cartilage defect repair in a rabbit model
por: Slimi, Fathia, et al.
Publicado: (2021)

Intra-articular low-dose parathyroid hormone (1-34) improves mobility and articular cartilage quality in a preclinical age-related knee osteoarthritis model
por: Chen, Chung-Hwan, et al.
Publicado: (2021)

The effect induced by alternated mechanical loading on Notch-1 in mandibular condylar cartilage of growing rabbits
por: Yan, Fan, et al.
Publicado: (2021)

Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint
por: Liao, Wen-ting, et al.
Publicado: (2022)

Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope
por: Hu, Wencheng, et al.
Publicado: (2022)

Bisphosphonate use is associated with a decreased joint narrowing rate in the non-arthritic hip
por: Kawai, Toshiyuki, et al.
Publicado: (2022)

Suramin enhances chondrogenic properties by regulating the p67(phox)/PI3K/AKT/SOX9 signalling pathway
por: Liu, Zi-Miao, et al.
Publicado: (2022)

Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways
por: Lu, Rui, et al.
Publicado: (2023)

Regeneration of injured articular cartilage using the recombinant human amelogenin protein
por: Helwa-Shalom, Omer, et al.
Publicado: (2023)

Comparative effect of platelet- and mesenchymal stromal cell-derived extracellular vesicles on human cartilage explants using an ex vivo inflammatory osteoarthritis model
por: Forteza-Genestra, Maria A., et al.
Publicado: (2023)

Effect of treadmill training on fibrocartilage complex repair in tendon-bone insertion healing in the postinflammatory stage
por: Tan, Jindong, et al.
Publicado: (2023)

Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4
por: Coles, Jeffrey M, et al.
Publicado: (2010)

Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo
por: Davidson, Rose K, et al.
Publicado: (2013)

Cartilage turnover and intra-articular corticosteroid injections in knee osteoarthritis
por: Klocke, Rainer, et al.
Publicado: (2018)

Contrast-Enhanced Computed Tomography Enables Quantitative Evaluation of Tissue Properties at Intrajoint Regions in Cadaveric Knee Cartilage
por: Stewart, Rachel C., et al.
Publicado: (2016)

Cartilage Quality (dGEMRIC Index) Following Knee Joint Distraction or High Tibial Osteotomy
por: Besselink, Nick J., et al.
Publicado: (2018)

Effect of Moderate Exercise on the Superficial Zone of Articular Cartilage in Age-Related Osteoarthritis
por: Yin, Yukun, et al.
Publicado: (2023)

HDAC4 mutant represses chondrocyte hypertrophy by locating in the nucleus and attenuates disease progression of posttraumatic osteoarthritis
por: Gu, Xiaodong, et al.
Publicado: (2022)

GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women
por: Williams, F M K, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_aoi6m44amlj0urbh4v1n4f6eks