Deep integrative models for large-scale human genomics

Polygenic risk scores (PRSs) are expected to play a critical role in precision medicine. Currently, PRS predictors are generally based on linear models using summary statistics, and more recently individual-level data. However, these predictors mainly capture additive relationships and are limited i...

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Detalles Bibliográficos
Autores principales: Sigurdsson, Arnór I, Louloudis, Ioannis, Banasik, Karina, Westergaard, David, Winther, Ole, Lund, Ole, Ostrowski, Sisse Rye, Erikstrup, Christian, Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, Bjarni J, Rasmussen, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325897/
https://www.ncbi.nlm.nih.gov/pubmed/37224538
http://dx.doi.org/10.1093/nar/gkad373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325897/
https://www.ncbi.nlm.nih.gov/pubmed/37224538
http://dx.doi.org/10.1093/nar/gkad373

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