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Deep integrative models for large-scale human genomics
Polygenic risk scores (PRSs) are expected to play a critical role in precision medicine. Currently, PRS predictors are generally based on linear models using summary statistics, and more recently individual-level data. However, these predictors mainly capture additive relationships and are limited i...
Autores principales: | Sigurdsson, Arnór I, Louloudis, Ioannis, Banasik, Karina, Westergaard, David, Winther, Ole, Lund, Ole, Ostrowski, Sisse Rye, Erikstrup, Christian, Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, Bjarni J, Rasmussen, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325897/ https://www.ncbi.nlm.nih.gov/pubmed/37224538 http://dx.doi.org/10.1093/nar/gkad373 |
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