Pyruvate Kinase M (PKM) binds ribosomes in a poly-ADP ribosylation dependent manner to induce translational stalling

In light of the numerous studies identifying post-transcriptional regulators on the surface of the endoplasmic reticulum (ER), we asked whether there are factors that regulate compartment specific mRNA translation in human cells. Using a proteomic survey of spatially regulated polysome interacting p...

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Detalles Bibliográficos
Autores principales: Kejiou, Nevraj S, Ilan, Lena, Aigner, Stefan, Luo, Enching, Tonn, Tori, Ozadam, Hakan, Lee, Muyoung, Cole, Gregory B, Rabano, Ines, Rajakulendran, Nishani, Yee, Brian A, Najafabadi, Hamed S, Moraes, Trevor F, Angers, Stephane, Yeo, Gene W, Cenik, Can, Palazzo, Alexander F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325899/
https://www.ncbi.nlm.nih.gov/pubmed/37224531
http://dx.doi.org/10.1093/nar/gkad440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325899/
https://www.ncbi.nlm.nih.gov/pubmed/37224531
http://dx.doi.org/10.1093/nar/gkad440

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