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Prediction of cooperative homeodomain DNA binding sites from high-throughput-SELEX data

Homeodomain proteins constitute one of the largest families of metazoan transcription factors. Genetic studies have demonstrated that homeodomain proteins regulate many developmental processes. Yet, biochemical data reveal that most bind highly similar DNA sequences. Defining how homeodomain protein...

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Detalles Bibliográficos
Autores principales: Cain, Brittany, Webb, Jordan, Yuan, Zhenyu, Cheung, David, Lim, Hee-Woong, Kovall, Rhett A, Weirauch, Matthew T, Gebelein, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325903/
https://www.ncbi.nlm.nih.gov/pubmed/37114997
http://dx.doi.org/10.1093/nar/gkad318