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Attenuation of a DNA cruciform by a conserved regulator directs T3SS1 mediated virulence in Vibrio parahaemolyticus

Pathogenic Vibrio species account for 3–5 million annual life-threatening human infections. Virulence is driven by bacterial hemolysin and toxin gene expression often positively regulated by the winged helix-turn-helix (wHTH) HlyU transcriptional regulator family and silenced by histone-like nucleoi...

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Detalles Bibliográficos
Autores principales: Getz, Landon J, Brown, Justin M, Sobot, Lauren, Chow, Alexandra, Mahendrarajah, Jastina, Thomas, Nikhil A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325908/
https://www.ncbi.nlm.nih.gov/pubmed/37158250
http://dx.doi.org/10.1093/nar/gkad370