Single-stranded DNA recruitment mechanism in replication origin unwinding by DnaA initiator protein and HU, an evolutionary ubiquitous nucleoid protein

The Escherichia coli replication origin oriC contains the initiator ATP-DnaA-Oligomerization Region (DOR) and its flanking duplex unwinding element (DUE). In the Left-DOR subregion, ATP-DnaA forms a pentamer by binding to R1, R5M and three other DnaA boxes. The DNA-bending protein IHF binds sequence...

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Detalles Bibliográficos
Autores principales: Yoshida, Ryusei, Ozaki, Shogo, Kawakami, Hironori, Katayama, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325909/
https://www.ncbi.nlm.nih.gov/pubmed/37178000
http://dx.doi.org/10.1093/nar/gkad389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325909/
https://www.ncbi.nlm.nih.gov/pubmed/37178000
http://dx.doi.org/10.1093/nar/gkad389

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