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Actin nucleators safeguard replication forks by limiting nascent strand degradation

Accurate genome replication is essential for all life and a key mechanism of disease prevention, underpinned by the ability of cells to respond to replicative stress (RS) and protect replication forks. These responses rely on the formation of Replication Protein A (RPA)-single stranded (ss) DNA comp...

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Detalles Bibliográficos
Autores principales: Nieminuszczy, Jadwiga, Martin, Peter R, Broderick, Ronan, Krwawicz, Joanna, Kanellou, Alexandra, Mocanu, Camelia, Bousgouni, Vicky, Smith, Charlotte, Wen, Kuo-Kuang, Woodward, Beth L, Bakal, Chris, Shackley, Fiona, Aguilera, Andrés, Stewart, Grant S, Vyas, Yatin M, Niedzwiedz, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325910/
https://www.ncbi.nlm.nih.gov/pubmed/37224534
http://dx.doi.org/10.1093/nar/gkad369