Formation of nuclear CPSF6/CPSF5 biomolecular condensates upon HIV-1 entry into the nucleus is important for productive infection

The early events of HIV-1 infection involve the transport of the viral core into the nucleus. This event triggers the translocation of CPSF6 from paraspeckles into nuclear speckles forming puncta-like structures. Our investigations revealed that neither HIV-1 integration nor reverse transcription is...

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Detalles Bibliográficos
Autores principales: Luchsinger, Charlotte, Lee, KyeongEun, Mardones, Gonzalo A., KewalRamani, Vineet N., Diaz-Griffero, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325960/
https://www.ncbi.nlm.nih.gov/pubmed/37414787
http://dx.doi.org/10.1038/s41598-023-37364-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325960/
https://www.ncbi.nlm.nih.gov/pubmed/37414787
http://dx.doi.org/10.1038/s41598-023-37364-x

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