Shared hotspot mutations in oncogenes position dogs as an unparalleled comparative model for precision therapeutics

Naturally occurring canine cancers have remarkable similarities to their human counterparts. To better understand these similarities, we investigated 671 client-owned dogs from 96 breeds with 23 common tumor types, including those whose mutation profile are unknown (anal sac carcinoma and neuroendoc...

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Detalles Bibliográficos
Autores principales: Rodrigues, Lucas, Watson, Joshua, Feng, Yuan, Lewis, Benjamin, Harvey, Garrett, Post, Gerald, Megquier, Kate, White, Michelle E., Lambert, Lindsay, Miller, Aubrey, Lopes, Christina, Zhao, Shaying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325973/
https://www.ncbi.nlm.nih.gov/pubmed/37414794
http://dx.doi.org/10.1038/s41598-023-37505-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325973/
https://www.ncbi.nlm.nih.gov/pubmed/37414794
http://dx.doi.org/10.1038/s41598-023-37505-2

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