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Multiomics analysis of naturally efficacious lipid nanoparticle coronas reveals high-density lipoprotein is necessary for their function

In terms of lipid nanoparticle (LNP) engineering, the relationship between particle composition, delivery efficacy, and the composition of the biocoronas that form around LNPs, is poorly understood. To explore this we analyze naturally efficacious biocorona compositions using an unbiased screening w...

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Detalles Bibliográficos
Autores principales: Liu, Kai, Nilsson, Ralf, Lázaro-Ibáñez, Elisa, Duàn, Hanna, Miliotis, Tasso, Strimfors, Marie, Lerche, Michael, Salgado Ribeiro, Ana Rita, Ulander, Johan, Lindén, Daniel, Salvati, Anna, Sabirsh, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325984/
https://www.ncbi.nlm.nih.gov/pubmed/37414857
http://dx.doi.org/10.1038/s41467-023-39768-9