Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity

As an important hydrolytic enzyme that yields 2-AG and free fatty acids, diacylglycerol lipase alpha (DAGLA) is involved in exacerbating malignant phenotypes and cancer progression, but the role of the DAGLA/2-AG axis in HCC progression remains unclear. Here, we found that the upregulation of compon...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Yu-Chuan, Meng, Guang-Xiao, Yang, Chun-Cheng, Yang, Ya-Fei, Tan, Si-Yu, Yan, Lun-Jie, Ding, Zi-Niu, Ma, Yun-Long, Dong, Zhao-Ru, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325985/
https://www.ncbi.nlm.nih.gov/pubmed/37414748
http://dx.doi.org/10.1038/s41419-023-05919-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325985/
https://www.ncbi.nlm.nih.gov/pubmed/37414748
http://dx.doi.org/10.1038/s41419-023-05919-5

Ejemplares similares