Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase

Diterpene synthase VenA is responsible for assembling venezuelaene A with a unique 5-5-6-7 tetracyclic skeleton from geranylgeranyl pyrophosphate. VenA also demonstrates substrate promiscuity by accepting geranyl pyrophosphate and farnesyl pyrophosphate as alternative substrates. Herein, we report t...

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Detalles Bibliográficos
Autores principales: Li, Zhong, Zhang, Lilan, Xu, Kangwei, Jiang, Yuanyuan, Du, Jieke, Zhang, Xingwang, Meng, Ling-Hong, Wu, Qile, Du, Lei, Li, Xiaoju, Hu, Yuechan, Xie, Zhenzhen, Jiang, Xukai, Tang, Ya-Jie, Wu, Ruibo, Guo, Rey-Ting, Li, Shengying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325987/
https://www.ncbi.nlm.nih.gov/pubmed/37414771
http://dx.doi.org/10.1038/s41467-023-39706-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325987/
https://www.ncbi.nlm.nih.gov/pubmed/37414771
http://dx.doi.org/10.1038/s41467-023-39706-9

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