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Linker histone variant H1.2 is a brake on white adipose tissue browning

Adipose-tissue is a central metabolic organ for whole-body energy homeostasis. Here, we find that highly expressed H1.2, a linker histone variant, senses thermogenic stimuli in beige and brown adipocytes. Adipocyte H1.2 regulates thermogenic genes in inguinal white-adipose-tissue (iWAT) and affects...

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Detalles Bibliográficos
Autores principales: Yuan, Yangmian, Fan, Yu, Zhou, Yihao, Qiu, Rong, Kang, Wei, Liu, Yu, Chen, Yuchen, Wang, Chenyu, Shi, Jiajian, Liu, Chengyu, Li, Yangkai, Wu, Min, Huang, Kun, Liu, Yong, Zheng, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325996/
https://www.ncbi.nlm.nih.gov/pubmed/37414781
http://dx.doi.org/10.1038/s41467-023-39713-w