Cargando…
Linker histone variant H1.2 is a brake on white adipose tissue browning
Adipose-tissue is a central metabolic organ for whole-body energy homeostasis. Here, we find that highly expressed H1.2, a linker histone variant, senses thermogenic stimuli in beige and brown adipocytes. Adipocyte H1.2 regulates thermogenic genes in inguinal white-adipose-tissue (iWAT) and affects...
Autores principales: | Yuan, Yangmian, Fan, Yu, Zhou, Yihao, Qiu, Rong, Kang, Wei, Liu, Yu, Chen, Yuchen, Wang, Chenyu, Shi, Jiajian, Liu, Chengyu, Li, Yangkai, Wu, Min, Huang, Kun, Liu, Yong, Zheng, Ling |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10325996/ https://www.ncbi.nlm.nih.gov/pubmed/37414781 http://dx.doi.org/10.1038/s41467-023-39713-w |
Ejemplares similares
-
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning
por: Ferrari, Alessandra, et al.
Publicado: (2017) -
Histone H1.2 promotes hepatocarcinogenesis by regulating signal transducer and activator of transcription 3 signaling
por: Wang, Qing, et al.
Publicado: (2022) -
Molecular and Cellular Functions of the Linker Histone H1.2
por: Lai, Shuting, et al.
Publicado: (2022) -
Cross-linkers both drive and brake cytoskeletal remodeling and furrowing in cytokinesis
por: Descovich, Carlos Patino, et al.
Publicado: (2018) -
Lung Cancer Therapy Targeting Histone Methylation: Opportunities and Challenges
por: Chen, Yuchen, et al.
Publicado: (2018)