Unbiased proteomics and multivariable regularized regression techniques identify SMOC1, NOG, APCS, and NTN1 in an Alzheimer’s disease brain proteomic signature

Advancements in omics methodologies have generated a wealth of high-dimensional Alzheimer’s disease (AD) datasets, creating significant opportunities and challenges for data interpretation. In this study, we utilized multivariable regularized regression techniques to identify a reduced set of protei...

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Detalles Bibliográficos
Autores principales: Roberts, Jackson A., Varma, Vijay R., Candia, Julián, Tanaka, Toshiko, Ferrucci, Luigi, Bennett, David A., Thambisetty, Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326005/
https://www.ncbi.nlm.nih.gov/pubmed/37414805
http://dx.doi.org/10.1038/s41514-023-00112-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326005/
https://www.ncbi.nlm.nih.gov/pubmed/37414805
http://dx.doi.org/10.1038/s41514-023-00112-6

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