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ASC- and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler’s murine encephalomyelitis virus

Theiler's murine encephalomyelitis virus (TMEV) induces an acute polioencephalomyelitis and a chronic demyelinating leukomyelitis in SJL mice. C57BL/6 (B6) mice generally do not develop TMEV-induced demyelinating disease (TMEV-IDD) due to virus elimination. However, TMEV can persist in specific...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Bühler, Melanie, Runft, Sandra, Gerold, Gisa, Marek, Katarzyna, Baumgärtner, Wolfgang, Strowig, Till, Gerhauser, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326010/
https://www.ncbi.nlm.nih.gov/pubmed/37414913
http://dx.doi.org/10.1038/s41598-023-38152-3