MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms

Robust identification of context-specific network features that control cellular phenotypes remains a challenge. We here introduce MOBILE (Multi-Omics Binary Integration via Lasso Ensembles) to nominate molecular features associated with cellular phenotypes and pathways. First, we use MOBILE to nomi...

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Detalles Bibliográficos
Autores principales: Erdem, Cemal, Gross, Sean M., Heiser, Laura M., Birtwistle, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326020/
https://www.ncbi.nlm.nih.gov/pubmed/37414767
http://dx.doi.org/10.1038/s41467-023-39729-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326020/
https://www.ncbi.nlm.nih.gov/pubmed/37414767
http://dx.doi.org/10.1038/s41467-023-39729-2

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