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MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms
Robust identification of context-specific network features that control cellular phenotypes remains a challenge. We here introduce MOBILE (Multi-Omics Binary Integration via Lasso Ensembles) to nominate molecular features associated with cellular phenotypes and pathways. First, we use MOBILE to nomi...
Autores principales: | Erdem, Cemal, Gross, Sean M., Heiser, Laura M., Birtwistle, Marc R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326020/ https://www.ncbi.nlm.nih.gov/pubmed/37414767 http://dx.doi.org/10.1038/s41467-023-39729-2 |
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