USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1

Ferroptosis is an iron-dependent form of regulated cell death characterized by lipid peroxidation. Colorectal cancer (CRC) cells evade ferroptosis despite their requirement of substantial iron and reactive oxygen species (ROS) to sustain active metabolism and extensive proliferation. However, the un...

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Detalles Bibliográficos
Autores principales: Duan, Junyi, Huang, Daoyuan, Liu, Cheng, Lv, Yangbo, Zhang, Lei, Chang, Fen, Zeng, Xiangyu, Li, Li, Wang, Weiping, Shao, Genze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326026/
https://www.ncbi.nlm.nih.gov/pubmed/37414755
http://dx.doi.org/10.1038/s41419-023-05915-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326026/
https://www.ncbi.nlm.nih.gov/pubmed/37414755
http://dx.doi.org/10.1038/s41419-023-05915-9

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