Citrullination of C1-inhibitor as a mechanism of impaired complement regulation in rheumatoid arthritis

BACKGROUND: Dysregulated complement activation, increased protein citrullination, and production of autoantibodies against citrullinated proteins are hallmarks of rheumatoid arthritis (RA). Citrullination is induced by immune cell-derived peptidyl-Arg deiminases (PADs), which are overactivated in th...

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Detalles Bibliográficos
Autores principales: Martin, Myriam, Nilsson, Sara C., Eikrem, David, Fromell, Karin, Scavenius, Carsten, Vogt, Leonie M., Bielecka, Ewa, Potempa, Jan, Enghild, Jan J., Nilsson, Bo, Ekdahl, Kristina N., Kapetanovic, Meliha C., Blom, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326043/
https://www.ncbi.nlm.nih.gov/pubmed/37426666
http://dx.doi.org/10.3389/fimmu.2023.1203506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326043/
https://www.ncbi.nlm.nih.gov/pubmed/37426666
http://dx.doi.org/10.3389/fimmu.2023.1203506

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