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Role of PDLIM1 in hepatic stellate cell activation and liver fibrosis progression

Liver fibrosis is caused by chronic hepatic injury and may lead to cirrhosis, and even hepatocellular carcinoma. When hepatic stellate cells (HSCs) are activated by liver injury, they transdifferentiate into myofibroblasts, which secrete extracellular matrix proteins that generate the fibrous scar....

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Detalles Bibliográficos
Autores principales: Ye, Bingyu, Yu, Mengli, Yue, Meijuan, Yin, Man, Zhang, Chunyan, Wang, Qiwen, Ding, Xinru, Shen, Wenlong, Zhao, Zhihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326060/
https://www.ncbi.nlm.nih.gov/pubmed/37414929
http://dx.doi.org/10.1038/s41598-023-38144-3