Cargando…

SERPINA3-ANKRD11-HDAC3 pathway induced aromatase inhibitor resistance in breast cancer can be reversed by HDAC3 inhibition

Endocrine resistance is a major challenge for breast cancer therapy. To identify the genes pivotal for endocrine-resistance progression, we screened five datasets and found 7 commonly dysregulated genes in endocrine-resistant breast cancer cells. Here we show that downregulation of serine protease i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Jing, Zhu, Mengdi, Wang, Qi, Deng, Yiyuan, Liu, Nianqiu, Liu, Yujie, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326080/
https://www.ncbi.nlm.nih.gov/pubmed/37414914
http://dx.doi.org/10.1038/s42003-023-05065-w