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Tofacitinib Reduces Spinal Inflammation in Vertebral Bodies and Posterolateral Elements in Ankylosing Spondylitis: Results from a Phase 2 Trial

INTRODUCTION: This post hoc analysis of phase 2 trial data assessed the efficacy of tofacitinib on magnetic resonance imaging (MRI) outcomes with the detailed anatomy-based Canada–Denmark (CANDEN) MRI scoring system and evaluated tofacitinib suppression of spinal inflammation in patients with active...

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Detalles Bibliográficos
Autores principales: Østergaard, Mikkel, Wu, Joseph, Fallon, Lara, Sherlock, Sarah P., Wang, Cunshan, Fleishaker, Dona, Kanik, Keith S., Maksymowych, Walter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326231/
https://www.ncbi.nlm.nih.gov/pubmed/37331992
http://dx.doi.org/10.1007/s40744-023-00564-y