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Targeting histone deacetylases for cancer therapy: Trends and challenges

Dysregulation of histone deacetylases (HDACs) is closely related to tumor development and progression. As promising anticancer targets, HDACs have gained a great deal of research interests and two decades of effort has led to the approval of five HDAC inhibitors (HDACis). However, currently traditio...

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Detalles Bibliográficos
Autores principales: Liang, Tao, Wang, Fengli, Elhassan, Reham M., Cheng, Yongmei, Tang, Xiaolei, Chen, Wengang, Fang, Hao, Hou, Xuben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326266/
https://www.ncbi.nlm.nih.gov/pubmed/37425042
http://dx.doi.org/10.1016/j.apsb.2023.02.007