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The effects of enhancing angiotensin converting enzyme in myelomonocytes on ameliorating Alzheimer’s-related disease and preserving cognition

This review examines the role of angiotensin-converting enzyme (ACE) in the context of Alzheimer’s disease (AD) and its potential therapeutic value. ACE is known to degrade the neurotoxic 42-residue long alloform of amyloid β-protein (Aβ(42)), a peptide strongly associated with AD. Previous studies...

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Detalles Bibliográficos
Autores principales: Danziger, Ron, Fuchs, Dieu-Trang, Koronyo, Yosef, Rentsendorj, Altan, Sheyn, Julia, Hayden, Eric Y., Teplow, David B., Black, Keith L., Fuchs, Sebastien, Bernstein, Kenneth E., Koronyo-Hamaoui, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326285/
https://www.ncbi.nlm.nih.gov/pubmed/37427403
http://dx.doi.org/10.3389/fphys.2023.1179315