Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disease. It is featured by abnormal alpha-synuclein (α-syn) aggregation in dopaminergic neurons in the substantia nigra. Macroautophagy (autophagy) is an evolutionarily conserved cellular process for degradation of cellular...

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Detalles Bibliográficos
Autores principales: Zhu, Qi, Song, Juxian, Chen, Jia-Yue, Yuan, Zhenwei, Liu, Liangfeng, Xie, Li-Ming, Liao, Qiwen, Ye, Richard D., Chen, Xiu, Yan, Yepiao, Tan, Jieqiong, Heng Tan, Chris Soon, Li, Min, Lu, Jia-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326294/
https://www.ncbi.nlm.nih.gov/pubmed/37425041
http://dx.doi.org/10.1016/j.apsb.2023.03.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326294/
https://www.ncbi.nlm.nih.gov/pubmed/37425041
http://dx.doi.org/10.1016/j.apsb.2023.03.011

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