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Corynoxine B targets at HMGB1/2 to enhance autophagy for α-synuclein clearance in fly and rodent models of Parkinson's disease
Parkinson's disease (PD) is the most common neurodegenerative movement disease. It is featured by abnormal alpha-synuclein (α-syn) aggregation in dopaminergic neurons in the substantia nigra. Macroautophagy (autophagy) is an evolutionarily conserved cellular process for degradation of cellular...
Autores principales: | Zhu, Qi, Song, Juxian, Chen, Jia-Yue, Yuan, Zhenwei, Liu, Liangfeng, Xie, Li-Ming, Liao, Qiwen, Ye, Richard D., Chen, Xiu, Yan, Yepiao, Tan, Jieqiong, Heng Tan, Chris Soon, Li, Min, Lu, Jia-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326294/ https://www.ncbi.nlm.nih.gov/pubmed/37425041 http://dx.doi.org/10.1016/j.apsb.2023.03.011 |
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