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Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer

Epigenetic therapies that cause genome-wide epigenetic alterations, could trigger local interplay between different histone marks, leading to a switch of transcriptional outcome and therapeutic responses of epigenetic treatment. However, in human cancers with diverse oncogenic activation, how oncoge...

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Detalles Bibliográficos
Autores principales: Wang, Xiaomin, Xu, Jun, Sun, Yiming, Cao, Siyuwei, Zeng, Hanlin, Jin, Nan, Shou, Matthew, Tang, Shuai, Chen, Yi, Huang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326305/
https://www.ncbi.nlm.nih.gov/pubmed/37425067
http://dx.doi.org/10.1016/j.apsb.2023.03.009