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A computational suite for the structural and functional characterization of amyloid aggregates

We developed the aggregate characterization toolkit (ACT), a fully automated computational suite based on existing and widely used core algorithms to measure the number, size, and permeabilizing activity of recombinant and human-derived aggregates imaged with diffraction-limited and super-resolution...

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Detalles Bibliográficos
Autores principales: Xia, Zengjie, Wu, Yunzhao, Lam, Jeff Yui Long, Zhang, Ziwei, Burke, Melanie, Fertan, Emre, Ranasinghe, Rohan T., Hidari, Eric, Danial, John S.H., Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326375/
https://www.ncbi.nlm.nih.gov/pubmed/37426747
http://dx.doi.org/10.1016/j.crmeth.2023.100499