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A computational suite for the structural and functional characterization of amyloid aggregates
We developed the aggregate characterization toolkit (ACT), a fully automated computational suite based on existing and widely used core algorithms to measure the number, size, and permeabilizing activity of recombinant and human-derived aggregates imaged with diffraction-limited and super-resolution...
Autores principales: | Xia, Zengjie, Wu, Yunzhao, Lam, Jeff Yui Long, Zhang, Ziwei, Burke, Melanie, Fertan, Emre, Ranasinghe, Rohan T., Hidari, Eric, Danial, John S.H., Klenerman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326375/ https://www.ncbi.nlm.nih.gov/pubmed/37426747 http://dx.doi.org/10.1016/j.crmeth.2023.100499 |
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