Single-cell RNA sequencing identifies distinct transcriptomic signatures between PMA/ionomycin- and αCD3/αCD28-activated primary human T cells

Immunologists have activated T cells in vitro using various stimulation methods, including phorbol myristate acetate (PMA)/ionomycin and αCD3/αCD28 agonistic antibodies. PMA stimulates protein kinase C, activating nuclear factor-κB, and ionomycin increases intracellular calcium levels, resulting in...

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Detalles Bibliográficos
Autores principales: Lee, Jung Ho, Lee, Brian H, Jeong, Soyoung, Joh, Christine Suh-Yun, Nam, Hyo Jeong, Choi, Hyun Seung, Sserwadda, Henry, Oh, Ji Won, Park, Chung-Gyu, Jin, Seon-Pil, Kim, Hyun Je
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326540/
https://www.ncbi.nlm.nih.gov/pubmed/37704208
http://dx.doi.org/10.5808/gi.23009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326540/
https://www.ncbi.nlm.nih.gov/pubmed/37704208
http://dx.doi.org/10.5808/gi.23009

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