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Evaluation of Leptospira interrogans knockdown mutants for LipL32, LipL41, LipL21, and OmpL1 proteins

INTRODUCTION: Leptospirosis is a worldwide zoonosis caused by pathogenic and virulent species of the genus Leptospira, whose pathophysiology and virulence factors remain widely unexplored. Recently, the application of CRISPR interference (CRISPRi) has allowed the specific and rapid gene silencing of...

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Detalles Bibliográficos
Autores principales: Fernandes, Luis G. V., Teixeira, Aline F., Nascimento, Ana L. T. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326724/
https://www.ncbi.nlm.nih.gov/pubmed/37426019
http://dx.doi.org/10.3389/fmicb.2023.1199660