Ruxolitinib inhibits the proliferation and induces the apoptosis of MLL-r ALL cells through inactivating JAK/STAT signaling pathway

BACKGROUND: The childhood patients with mixed-lineage leukemia rearrangement (MLL-r) gene have worse outcome than non-MLL, and thus often treated with high-risk chemotherapy regimens, so targeted therapy is important for this type of leukemia. This purpose of study was to explore the effects of ruxo...

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Detalles Bibliográficos
Autores principales: Liao, Xiong-Yu, Zhou, Dun-Hua, Fang, Jian-Pei, Qiu, Kun-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326758/
https://www.ncbi.nlm.nih.gov/pubmed/37427069
http://dx.doi.org/10.21037/tp-23-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326758/
https://www.ncbi.nlm.nih.gov/pubmed/37427069
http://dx.doi.org/10.21037/tp-23-16

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