Homologous recombination pathway gene variants identified by tumor-only sequencing assays in lung carcinoma patients

BACKGROUND: The homologous recombination (HR) repair pathway plays a key role in double-stranded DNA break repair, and germline HR pathway gene variants are associated with increased risk of several cancers, including breast and ovarian cancer. HR deficiency is also a therapeutically targetable phen...

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Detalles Bibliográficos
Autores principales: Yoon, Ju-Yoon, Roth, Jacquelyn J., Rushton, Chase A., Morrissette, Jennifer J. D., Nathanson, Katherine L., Cohen, Roger B., Rosenbaum, Jason N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326790/
https://www.ncbi.nlm.nih.gov/pubmed/37425424
http://dx.doi.org/10.21037/tlcr-22-749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10326790/
https://www.ncbi.nlm.nih.gov/pubmed/37425424
http://dx.doi.org/10.21037/tlcr-22-749

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